Epidural clonidine applied as an adjunct to local anesthetics has 3 distinct mechanisms of action. To start with, the stimulation of alpha-two-receptors during the dorsal horn reduces pain transmission. Secondly, clonidine could cause nearby vasoconstriction that restrictions vascular elimination of regional epidural anesthetics. : connected to, served by, or https://andrewa803cau1.wikinstructions.com/user