It is feasible that the TCAB1-mediated “switch” just isn't captured from the conformation characterized in the cryo-EM structure. Characterizing a higher portion of the holoenzyme particles during the Energetic chromatographic fraction will likely lead to the identification of supplemental conformational states. The cryo-EM characterization of human telomerase also reveals the https://pietv479qle5.blogmazing.com/profile